教員情報 - 髙橋　浩之

学位

博士（医学）

刊行論文

1.	原著	Attempts to optimize postinduction treatment in childhood acute myeloid leukemia without core-binding factors: A report from the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) 2020/12
2.	原著	Impact of immunophenotypic characteristics on genetic subgrouping in childhood acute lymphoblastic leukemia: Tokyo Children's Cancer Study Group (TCCSG) study L04-16. 2020/10
3.	原著	Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia 2020/10
4.	原著	Predisposition to prolonged neutropenia after chemotherapy for paediatric acute myeloid leukaemia is associated with better prognosis in the Japanese Paediatric Leukaemia/Lymphoma Study Group AML-05 study 2020/04
5.	症例報告	Acute promyelocytic leukemia with a cryptic insertion of RARA into TBL1XR1. 2019/07/27
6.	原著	Clinical and molecular characteristics of MEF2D fusion-positive precursor B-cell acute lymphoblastic leukemia in childhood, including a novel translocation resulting in MEF2D-HNRNPH1 gene fusion. 2019/01
7.	原著	Recurrent RARB Translocations in Acute Promyelocytic Leukemia Lacking RARA Translocation. 2018/08
8.	原著	Treatment outcome of children with acute lymphoblastic leukemia: the Tokyo Children's Cancer Study Group (TCCSG) Study L04-16. 2018/07
9.	原著	Performance of multiplex fusion gene testing in pediatric acute myeloid leukemia 2018/01
10.	原著	Risk-stratified therapy for children with FLT3-ITD-positive acute myeloid leukemia: results from the JPLSG AML-05 study 2018/01
11.	症例報告	Crizotinib treatment for refractory pediatric acute myeloid leukemia with RAN-binding protein 2-anaplastic lymphoma kinase fusion gene 2016/08
12.	症例報告	Fatal warm autoimmune hemolytic anemia in a child due to IgM-type autoantibodies 2016/08
13.	原著	High event-free survival rate with minimum-dose-anthracycline treatment in childhood acute promyelocytic leukaemia: A nationwide prospective study by the Japanese Paediatric Leukaemia/Lymphoma Study Group 2016/08
14.	原著	Residual disease detected by multidimensional flow cytometry shows prognostic significance in childhood acute myeloid leukemia with intermediate cytogenetics and negative FLT3‑ITD: a report from the Tokyo Children's Cancer Study Group 2016/04
15.	総説	Acute myeloid leukemia in children - Current status and future directions. 2016/02
16.	原著	Preserved high probability of overall survival with significant reduction of chemotherapy for myeloid leukemia in Down syndrome: A nationwide prospective study in Japan. 2016/02
17.	原著	Outcome of adolescent patients with acute myeloid leukemia treated with pediatric protocols. 2015/09
18.	症例報告	TKI dasatinib monotherapy for a patient with Ph-like ALL bearing ATF7IP/PDGFRB translocation. 2014/11
19.	原著	Acute myeloid leukaemia with myelodysplastic features in children: a report of Japanese Paediatric Leukaemia/Lymphoma Study Group. 2014/10
20.	原著	Prognostic impact of gained chromosomes in high-hyperdiploid childhood acute lymphoblastic leukemia: a collaborative retrospective study of the Tokyo Children's Cancer Study Group (TCCSG) and Japan Association of Childhood Leukemia Study (JACLS) 2014/07
21.	原著	ATF7IP as a novel PDGFRB fusion partner in acute lymphoblastic leukemia in children. 2014/06
22.	原著	Excess treatment reduction including anthracyclines results in higher incidence of relapse in core binding factor acute myeloid leukemia in children. 2013/12
23.	原著	Influence of pre-hydration and pharmacogenetics on plasma methotrexate concentration and renal dysfunction following high-dose methotrexate therapy. 2013/12
24.	原著	Appropriate dose reduction in induction therapy is essential for the treatment of infants with acute myeloid leukemia: a report from the Japanese Pediatric Leukemia/Lymphoma Study Group. 2013/11
25.	原著	小児急性前骨髄球性白血病に対する三酸化ヒ素による治療 2013/04
10件表示
全件表示(25件)

著書

1.	部分執筆	Acute Myeloid Leukemia, Hematological Disorders in Children Pathogenesis and Treatment 2017/06
2.	部分執筆	播種性血管内凝固症候群―急性前骨髄球性白血病を含めて「小児内科　特集．プライマリ・ケア医が知っておくべき小児悪性疾患」 2017/12
3.	部分執筆	免疫性溶血性貧血「小児疾患診療のための病態生理3」 2016/11
4.	部分執筆	小児APLの標準的治療は何か「小児白血病・リンパ腫診療ガイドライン2016年版」 2016/02
5.	部分執筆	リンパ節腫大・肝腫大・脾腫大「小児血液・腫瘍学」 2015/11
6.	部分執筆	「輸血」「小児期の血液」「赤血球の異常（貧血）」「白血球の異常」「ナースの小児科学（改訂6版）」 2015/03
7.	部分執筆	「実践小児薬用量ガイド」 2014/07

学会発表

1.	Clinical characteristics and outcome of pediatric acute myeloid leukemia with 5q- : a report from the Japanese Leukemia/Lymphoma Study Group （口頭，一般） 2016/06/09
2.	小児急性前骨髄性白血病に対するカスタムパネルを用いた網羅的遺伝子解析（口頭，一般） 2020/11/20
3.	Acute promyelocytic leukemia with a cryptic insertion of RARA into TBL1XR1．（口頭，一般） 2018/12/14
4.	Correlation between obesity and outcome in patients with AML enrolled in the JPLSG AML-05 study. （口頭，一般） 2018/12/14
5.	RARB translocations in RARA-negative acute promyelocytic leukemia. （口頭，一般） 2018/12/14
6.	The Prognostic Value of TP53 Mutations Depends on Clinical Backgrounds in Pediatric Patients with Acute Lymphoblastic Leukemia. （ポスター掲示，一般） 2018/12/01
7.	Germline Genetic Predispositions to Secondary Malignant Neoplasms in Children. （口頭，一般） 2018/11/18
8.	Prognostic Impact of Neutropenia Period in Patients with Acute Myeloid Leukemia (AML) Enrolled in the Japanese Pediatric Leukemia/Lymphoma Study Group AML-05 Study. （口頭，一般） 2018/11/18
9.	TCCSG L04-16研究における近年同定された遺伝子異常を有する急'性リンパ芽球性白血病患児の治療予後（口頭，一般） 2018/11/16
10.	Effectiveness of Supportive Care Measurements to Reduce Infections During Induction for Children with Acute Myeloid Leukemia: A Report From the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) （ポスター掲示，一般） 2017/12/09
11.	RARB translocations in acute promyelocytic leukemia without RARA translocation （口頭，一般） 2017/12/09
12.	Treatment outcome of children with acute lymphoblastic leukemia: Results from TCCSG Study L04-16 （口頭，一般） 2017/10/21
13.	小児の急性前骨髄球性白血病（口頭，特別講演・招待講演など） 2017/10/07
14.	Risk-oriented therapy for Myeloid leukemia of Down syndrome: A Nationwide prospective study by the Japanese Pediatric Leukemia / Lymphoma Study Group (JPLSG). （ポスター掲示，一般） 2014/12/12
15.	Outcome of adolescent and young adults with acute myeloid leukemia treated with pediatric protocols: A report from the 3 Japanese cooperative studies. （口頭，一般） 2014/12/11
16.	High event-free survival rate with minimum-dose-anthracycline treatment in childhood acute promyelocytic leukemia: A nationwide prospective study by the Japanese Pediatric Leukemia / Lymphoma Study Group (JPLSG). （ポスター掲示，一般） 2014/12/10
17.	The prognostic relevance of the 2008 WHO classification of myeloid neoplasms in childhood acute myeloid leukemia. （ポスター掲示，一般） 2014/06/01
18.	Infant Stage4S Neuroblastoma with MYCN Amplification （ポスター掲示，一般） 2014/05/15
19.	Poor prognosis with different induction rate was observed in children with acute myeloid leukemia and FLT3-ITD according to the ITD/WT ratio: A result from the Japanede Pediatric Leukemia/Lymphoma Study Group. （ポスター掲示，一般） 2013/12
20.	Significance Of Minimal Residual Disease Detected By Multi-Color Flow Cytometry In Childhood Acute Myeloid Leukemia With The Intermideate-Risk Cytogenetics and Negative FMS-Like Tyrosine Kinase 3 Internal Tandem Duplication: A Report Of The Tokyo Children's Cancer Study Group. （ポスター掲示，一般） 2013/12
10件表示
全件表示(20件)

学歴

1.

1980/04～1986/03

京都府立医科大学医学部卒業医学博士

職歴

1.	2013/04～2022/03	東邦大学医学部医学科（大森病院）准教授
2.	2022/04～	東邦大学医学部医学科（大森病院）臨床教授

研究課題・受託研究・科研費

1.	2012/04～	小児骨髄系腫瘍に対する標準的治療法の確立
2.	2017/04～	新規診断小児急性前骨髄球性白血病の標準リスク群における化学療法薬全廃、及び高リスク群における化学療法薬減量を目指した第２相国際共同臨床試験開発を目指した臨床試験立案研究