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（最終更新日：2023-12-02 08:10:33）

  ノグチ　シュウジ   Noguchi Shuji
  野口　修治
   所属   東邦大学薬学部薬学科

職種教授

学位

博士（薬学、東京大学）

刊行論文

1.	原著	Characterization of Ambroxol and Its Hydrochloride Salt Crystals by Bromine K-Edge X-Ray Absorption Near-Edge Structure Spectroscopy and X-Ray Crystal Structure Analysis 2023/09/01
2.	原著	Cocrystal or Salt Crystallization for Active Pharmaceutical Ingredients By Using Deep Eutectic Solvents 2023/08/18
3.	原著	Novel Pharmaceutical Cocrystals and Solvate Crystals of Nobiletin, a Citrus Flavonoid with Potent Pharmacological Activity 2023/08/01
4.	原著	Comparison of the physical properties of disodium etidronate amorphous forms prepared by different manufacturing methods 2023/02/15
5.	原著	Analysis of cimetidine crystal polymorphs by X-ray absorption near-edge spectroscopy. 2022/12/23
6.	原著	Direct detection of the crystal form of active pharmaceutical ingredients in tablets by X-ray absorption fine structure spectroscopy 2022/08/09
7.	原著	C–H···S hydrogen bonds in ampicillin and amoxicillin crystals investigated by sulfur K-edge X-ray absorption near-edge structure spectroscopy and single-crystal X-ray structure analysis 2022/08/07
8.	原著	Bromine K-edge X-ray absorption near-edge structure analysis on hydrobromide-salt crystals and the solid dispersion of active pharmaceutical ingredients 2022/02/01
9.	原著	Salt co-crystallization of loxoprofen sodium with sugar: Reduction of the propensity for hydrate formation by forming a continuous one-dimensional chain structure of sodium and sugar 2021/12/28
10.	原著	Investigation of Physical Properties of Disodium Etidronate Tetrahydrate and Application of Phosphorus K-Edge X-Ray Absorption Near-Edge Structure Spectroscopy 2021/12/17
11.	原著	Reduced deliquescency of isosorbide by cocrystallization and mechanisms for hygroscopicity 2021/09/25
12.	原著	X‑ray Absorption Near-Edge Spectroscopy Analysis of Indomethacin in Crystalline Forms and in Amorphous Solid Dispersions 2021/08/10
13.	原著	Chlorine K‑Edge X‑ray Absorption Near-Edge Structure Discrimination of Crystalline Solvates and Salts in Organic Molecules 2020/07/22
14.	原著	Chlorine K-Edge X-Ray Absorption Near-Edge Structure Analysis of Clarithromycin Hydrochloride Metastable Crystal 2020/05
15.	原著	Correlation between drug dissolution and resistance to water-induced phase separation in solid dispersion formulations revealed by solid-state NMR spectroscopy 2020/03
16.	原著	Structural and biochemical basis of the formation of isoaspartate in the complementarity-determining region of antibody 64M-5 Fab 2019/12
17.	原著	Crystal structures of flavone C-glycosides from oolong tea leaves: chafuroside A dihydrate and chafuroside B monohydrate. 2019/09
18.	原著	Desolvation behavior of indinavir sulfate ethanol and follow-up by terahertz spectroscopy 2019/08
19.	原著	Mechanism of drug release from temperature-sensitive formulations composed of low-melting-point microcrystalline wax. 2019/06
20.	原著	Structures of the antibody 64M-5 Fab and its complex with dT(6–4)T indicate induced-fit and high-affinity mechanisms. 2019/02
21.	原著	Phase transitions of antibiotic clarithromycin forms I, IV and new form VII crystals 2018/08
22.	原著	Mechanism of the formation of hollow spherical granules using a high shear granulator. 2018/05
23.	原著	Stabilization Mechanism of Roxithromycin Tablets Under Gastric pH Conditions. 2018/05
24.	原著	Morphological and physicochemical evaluation of two distinct glibenclamide/hypromellose amorphous nanoparticles prepared by the antisolvent method 2018/04
25.	原著	New scale-down methodology from commercial to lab scale to optimize plant-derived soft gel capsule formulations on a commercial scale. 2018/01
26.	原著	Melt adsorption as a manufacturing method for fine particles of wax matrices without any agglomerates 2017/08
27.	原著	Effect of gel formation on the dissolution behavior of clarithromycin tablets. 2017/04
28.	原著	Mechanisms for Improved Hygroscopicity of L-Arginine Valproate Revealed by X-Ray Single Crystal Structure Analysis 2017/03
29.	原著	Enhancing the solubility and oral bioavailability of poorly water-soluble drugs using monoolein cubosomes 2017/01
30.	原著	Evaluation of the thermosensitive release properties of microspheres containing 2017/01
31.	原著	Application of terahertz attenuated total reflection spectroscopy to detect changes in the physical properties of lactose during the lubrication process required for drug formulation 2016/12
32.	原著	Structure of anti-tumor drug 7-ethyl-10-hydroxycamptothecin monohydrate and its solid state hydrolysis mechanism on heating 2016/12
33.	原著	Saturated fatty acids and fatty acid esters promote the polymorphic transition of clarithromycin metastable form I crystal 2016/10
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全件表示(33件)

著書

1.	部分執筆	「製剤学・物理薬剤学通論第2版」 2021/09/06
2.	部分執筆	「製剤学・物理薬剤学通論」 2019/09

プロフィール

学歴

1.		東京大学大学院薬学系研究科博士（薬学）
2.	1989/04～1991/03	東京大学大学院薬学系研究科機能薬学専攻修士課程修了薬学修士
3.	1985/04～1989/03	東京大学薬学部卒業

職歴

2016/04～

東邦大学薬学部薬学科教授

現在の専門分野

薬系分析、物理化学, 医療薬学　（キーワード：物理薬剤学，製剤学）

ホームページ

https://www.lab.toho-u.ac.jp/phar/yakuzai/index.html