オバラ　チズカ   Obara Chizuka   小原　千寿香    所属   東邦大学  理学部 生物学科    職種   博士研究員
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Ink Jet Three-Dimensional Digital Fabrication for Biological Tissue Manufacturing: Analysis of Alginate Microgel Beads Produced by Ink Jet Droplets for Three Dimensional Tissue Fabrication
掲載誌名	正式名：JOURNAL OF IMAGING SCIENCE AND TECHNOLOGY ISSNコード：1062-3701
出版社	I S & T - SOC IMAGING SCIENCE TECHNOLOGY
巻・号・頁	52(6),pp.60201-1-60201-6(6)
著者・共著者	Makoto Nakamura,Yuichi Nishiyama,Chizuka Henmi,Shintaroh Iwanaga,Hidemoto Nakagawa,Kumiko Yamaguchi,Keiichi Akita,Shuichi Mochizuki,Koki Takiura
発行年月	2008/11
概要	Ink jet technology has advantages such as high-resolution and a multicolor printing capability and has a good potential for computer-based three-dimensional (3D) fabrication. The authors have developed an ink jet 30 bioprinter to manufacture biologically viable 3D structures using living cells. They have developed an effective method for the fabrication of 3D hydrogel structures by using ink jet technology with a liquid aqueous gelating medium, which is essential in fabricating 3D structures with living cells. In the present study, they evaluated the feasibility of the ink jet approach for digital 3D biofabrication, analyzing the microgel beads produced by the ink jet droplets. The ink jet droplets of sodium alginate solution, which were ejected into CaCl(2) solution, gelled to form microgel beads. The resulting beads were analyzed by means of image-based particle analysis to show that homogeneously sized microgel beads were effectively produced. Ink jet 3D biofabrication has a high potential for effective digital fabrication with such homogeneous microgel beads and will provide promising approaches for sophisticated computer assisted tissue engineering. (c) 2008 Society for Imaging Science and Technology.
DOI	10.2352/J.ImagingSci.Technol.(2008)52:6(060201)