(最終更新日:2020-01-27 16:56:47)
  タイラ タカヒロ   Taira Takahiro
  平 敬宏
   所属   東邦大学  医学部 医学科
   職種   教授

学位


博士(薬学)

刊行論文


1. 原著  Protection against oxidative stress-induced neurodegeneration by a modulator for DJ-1, a wild-type of familial Parkinson's disease-linked PARK7. 2009/10
2. 原著  Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury. 2009/11
3. 原著  Neuroprotective effect of the antiparkinsonian drug pramipexole against nigrostriatal dopaminergic degeneration in rotenone-treated mice. 2009/12
4. 原著  Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN. 2009/11
5. 原著  DJ-1 binds to mitochondrial complex I and maintains its activity. 2009/11
6. 原著  Oxidative neurodegeneration is prevented by UCP0045037, an allosteric modulator for the reduced form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7. 2009/12
7. 原著  The protocadherins, PCDHB1 and PCDH7, are regulated by MeCP2 in neuronal cells and brain tissues: implication for pathogenesis of Rett syndrome. 2011/04
8. 原著  Protection against dopaminergic neurodegeneration in Parkinson's disease-model animals by a modulator of the oxidized form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7. 2011/05
9. 原著  The Ubiquitin System and Kaposi's Sarcoma-Associated Herpesvirus. 2012/02
10. 原著  The effects of heat shock protein 90 inhibitors on apoptosis and viral replication in primary effusion lymphoma cells. 2012/05
全件表示(11件)

学会発表


1. Human DJ-1-dependent activation of dopamine biosynthesis through interction of tyrosine hydroxylase with DJ-1 (口頭,一般) 2009/12/09
2. Inhibition of PTEN phosphatase activity by the direct interaction of DJ-1 with PTEN under the oxidative conditions (口頭,一般) 2009/09/16
3. ヒトDJ-1特異的なチロシン水酸化酵素遺伝子の転写活性化調節 (口頭,一般) 2010/09/03
4. がんウイルスによるアポトーシス制御因子p32/HABP1/ gC1qRの機能阻害 (ポスター掲示,一般) 2010/09/03
5. Identification of MeCP2-targetsynaptic molecules associated with pathogenesis of Rett syndrome (口頭,一般) 2010/12/08
6. 家族性パーキンソン病(PARK7)原因遺伝子産物DJ-1タンパク質の生物種差 (口頭,特別講演・招待講演など) 2010/09/03
プロフィール

職歴


1. 2013/04~ 東邦大学 医学部 医学科 教授

所属学会


1. 2018/04~ 日本医学教育学会