ハセガワ マコト   Hasegawa Makoto
  長谷川 誠
   所属   東邦大学  医学部 医学科(大橋病院)
   職種   助教
言語種別 英語
発表タイトル Detection of Chelated GBCA in Human Postmortem Brain and Bone Tissue;
Distribution by different chelate species
会議名 American Society of Neuroradiology 56th Annual Meeting
学会区分 国際学会
発表形式 口頭
講演区分 一般
発表者・共同発表者Makoto Hasegawa, Clay Davis, Luis Gonzalez-Cuyar, Debra Ellisor, Donna Roberts, Kenneth Maravilla
発表年月日 2018/06/06
開催地
(都市, 国名)
Vancouver, Canada
概要 HILIC was able to identify GBCA in chelated form in human brain and bone samples after exposure to GBCA.
All macrocyclic GBCA exposure to recovered from all tissue.
Linear agents were detected less frequently and were not recovered from all tissues. Linear chelates appeared to be recovered in lower amounts despite the total elemental gadolinium being present at higher level.
Further studies are needed to determine other chemical forms including gadolinium salts and macromolecules that are deposited in addition to intact GBCA.