教員情報 - 密田　亜希

ミツダ　アキ Mitsuda Aki 密田　亜希所属東邦大学医学部医学科（大森病院）職種助教
言語種別	英語
発表タイトル	Availability of Constrast Enhanced Ultrasound Using Sonazoid for the Breast Cancer Patients Treated with Neoadjuvant Chemotherapy.
会議名	12th World Congress of the World Federation for Ultrasound in Medicine and Biology
学会区分	国際学会
発表形式	口頭
講演区分	一般
発表者・共同発表者	◎Mitsuzuka Y†, Kanazawa S†, Ogata H†, Magoshi S†, Mitsuda A†, Shibuya K†, Kaneko H†
発表年月日	2009/09/02
開催地（都市, 国名）	Sydney, Australia
概要	We recently use contrast enhanced ultrasound (CEUS) using Sonazoid to evaluate an effect of neoadjuvant chemotherapy (NAC). In this study we introduce 2 cases of breast cancer who received NAC, and indicate an availability of CEUS for an evaluation of treatment effect. Case1: 46 years old female. A tumor (424129mm) was detected by ultrasound at AC region of the left breast. The tumor was diagnosed as a solid-tubular carcinoma by needle biopsy. Before NAC, strong contrast image was observed inside the tumor by CEUS, but as therapy strong contrast image reduced gradually. At the end point of NAC, tumor size was reduced to 13115mm and also strong contrast image inside the tumor almost disappeared. Surgical resection was performed after NAC, ultimately NAC effect was identified as a pathological complete response (pCR). Case2: 49 years old female. A tumor (261612 mm) was detected by ultrasound at CD region of the right breast. The tumor was diagnosed as a scirrhous carcinoma by needle biopsy. Before NAC, contrast image was observed only at the tumor margin. After NAC, the tumor size was reduced to 16117mm, but contrast image was still remained in the tumor. Surgical resection was performed after NAC, malignant cells were still remained in the tumor and ultimately NAC effect was identified as a partial response (PR). We experienced 2 remarkable cases, it suggest that the effect of treatment by NAC correlated with the decrease of the contrast image by CEUS. Therefore, CEUS using Sonazoid may contribute to evaluate an effect of NAC for breast cancer patient.