フルタ　トシアキ   Furuta Toshiaki   古田　寿昭    所属   東邦大学  理学部 生物分子科学科    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Development of the 8-aza-3-bromo-7-hydroxycoumarin-4-ylmethyl group as a new entry of photolabile protecting groups
掲載誌名	正式名：Tetrahedron
掲載区分	国外
巻・号・頁	70(29),pp.4400-4404
著者・共著者	H. Takano, T. Narumi, N. Ohashi, A. Suzuki, T. Furuta, W. Nomura, H. Tamamura
発行年月	2014/07/22
概要	A significant substitution effect of the position of the bromo group on the photosensitivity of the 8-azacoumarin chromophore leads to the development of a highly photosensitive 8-aza-3-bromo-7-hydroxycoumarin-4-ylmethyl (aza-3-Bhc) group that shows excellent photolytic efficiency and hydrophilicity with long-wavelength absorption maxima. The newly identified aza-3-Bhc group can be applied to caged glutamates for ester-type and carbamate-type protections of carboxyl and amino functionalities. (C) 2014 Elsevier Ltd. All rights reserved.