サカイ　ケン   Sakai Ken   酒井　謙    所属   東邦大学  医学部 医学科（大森病院）    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Combined Therapy with Peritoneal Dialysis and Hemodialysis: A Multicenter Retrospective Observational Cohort Study in Japan
掲載誌名	正式名：Blood purification 略　 称：Blood Purif ISSNコード：02535068/14219735
出版社	Karger
巻・号・頁	38(2),pp.149-153
著者・共著者	Maruyama Y.a, b · Yokoyama Ka, b · Nakayama M.c · Higuchi C.d · Sanaka T.d · Tanaka Y.e · Sakai K.e · Mizuiri S.e · Otsuka Y.a · Kuriyama S.a · Maeba T.f · Iwasawa H.g · Nakao T.g · Hosoya T.b · for the EARTH (Evaluation of the Adequacy of Renal replacement THerapy) study group
発行年月	2014/06
概要	Combining peritoneal dialysis (PD) and hemodialysis (HD) has been common treatment option in Japan. Methods: In this retrospective, multicenter, observational study, the clinical characteristics and outcomes of 104 patients (57 w 11 years, males 72) who had switched from PD alone to combined therapy with PD and HD were studied. Clinical parameters were measured at baseline and after 3 months of combined therapy. Results: At baseline, urine volume, dialysate-to-plasma ratio of creatinine (D/P Cr), and total Kt/V were 150 ml/day (range: 0-2,000 ml/day), 0.67 w 0.11, and 1.8 w 0.4, respectively. During the first 3 months of combined therapy, body weight, urine volume, serum creatinine level, and D/P Cr decreased, whereas hemoglobin levels increased. Conclusions: In patients where PD does not result in acceptable outcomes, combined therapy with PD and HD may have potential benefits in terms of dialysis adequacy and hydration status.
DOI	10.1159/000368389