ホリ　マサアキ   Hori Masaaki   堀　正明    所属   東邦大学  医学部 医学科（大森病院）    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Scan-rescan and inter-vendor reproducibility of neurite orientation dispersion and density imaging metrics.
掲載誌名	正式名：Neuroradiology 略　 称：Neuroradiology ISSNコード：14321920/00283940
掲載区分	国外
巻・号・頁	62(4),pp.483-494
著者・共著者	Andica C, Kamagata K, Hayashi T, Hagiwara A, Uchida W, Saito Y, Kamiya K, Fujita S, Akashi T, Wada A, Abe M, Kusahara H, Hori M†, Aoki S
発行年月	2020/04
概要	PURPOSE:The reproducibility of neurite orientation dispersion and density imaging (NODDI) metrics in the human brain has not been explored across different magnetic resonance (MR) scanners from different vendors. This study aimed to evaluate the scan-rescan and inter-vendor reproducibility of NODDI metrics in white and gray matter of healthy subjects using two 3-T MR scanners from two vendors.METHODS:Ten healthy subjects (7 males; mean age 30 ± 7 years, range 23-37 years) were included in the study. Whole-brain diffusion-weighted imaging was performed with b-values of 1000 and 2000 s/mm2RESULTS:The scan-rescan and inter-vendor reproducibility of NODDI metrics (intracellular volume fraction and orientation dispersion index) were comparable with those of diffusion tensor imaging (DTI) metrics. However, the inter-vendor reproducibilities of NODDI (CoV = 2.3-14%) were lower than the scan-rescan reproducibility (CoV: scanner A = 0.8-3.8%; scanner B = 0.8-2.6%). Compared with the finding of DTI metrics, the reproducibility of NODDI metrics was lower in white matter and higher in gray matter.CONCLUSION:The lower inter-vendor reproducibility of NODDI in some brain regions indicates that data acquired from different MRI scanners should be carefully interpreted.
DOI	10.1007/s00234-019-02350-6
PMID	31883043