コモリ コウジ   Komori Kouji
  小森 光二
   所属   東邦大学  医学部 医学科
   職種   助教
論文種別 原著
言語種別 英語
査読の有無 査読なし
表題 Molecular Analysis of bla KPC-2 -Harboring Plasmids: Tn 4401a Interplasmid Transposition and Tn 4401a -Carrying ColRNAI Plasmid Mobilization from Klebsiella pneumoniae to Citrobacter europaeus and Morganella morganii in a Single Patient
掲載誌名 正式名:mSphere
ISSNコード:2379-5042
掲載区分国外
出版社 American Society for Microbiology
巻・号・頁 6(6),pp.e0085021
著者・共著者 Kayoko Sugita,Kotaro Aoki,Kohji Komori,Tatsuya Nagasawa,Yoshikazu Ishii,Satoshi Iwata,Kazuhiro Tateda
発行年月 2021/12/22
概要 <jats:p>
Plasmid transfer plays an important role in the interspecies spread of carbapenemase genes, including the
<jats:named-content content-type="genus-species">Klebsiella pneumoniae</jats:named-content>
carbapenemase (KPC)-coding gene,
<jats:italic>bla</jats:italic>
<jats:sub>KPC</jats:sub>
. We conducted whole-genome sequencing (WGS) analysis and transmission experiments to analyze
<jats:italic>bla</jats:italic>
<jats:sub>KPC-2</jats:sub>
-carrying mobile genetic elements (MGEs) between the
<jats:italic>bla</jats:italic>
<jats:sub>KPC-2</jats:sub>
-harboring
<jats:named-content content-type="genus-species">K. pneumoniae</jats:named-content>
,
<jats:named-content content-type="genus-species">Citrobacter europaeus</jats:named-content>
, and
<jats:named-content content-type="genus-species">Morganella morganii</jats:named-content>
strains isolated from a single patient.
<jats:italic>bla</jats:italic>
<jats:sub>KPC-2</jats:sub>
was contained within an MGE, Tn
<jats:italic>4401a</jats:italic>
.
</jats:p>
DOI 10.1128/msphere.00850-21
ORCIDのPut Code 113478300
PMID 34730375