コモリ　コウジ   Komori Kouji   小森　光二    所属   東邦大学  医学部 医学科    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読なし
表題	A case of vertebral osteomyelitis with an erector spinae abscess caused by Staphylococcus argenteus ST1223.
掲載誌名	正式名：Japanese journal of infectious diseases
掲載区分	国内
著者・共著者	Yusuke Watanabe,Naoto Takenoshita,Maki Tsuchiya,Yuri Miura,Kohji Komori,Tetsuo Yamaguchi,Itaru Nakamura,Hidehiro Watanabe,Soichiro Shimizu
発行年月	2025/09/30
概要	Staphylococcus argenteus is a novel bacterial species distinct from Staphylococcus aureus. Nevertheless, S. argenteus is often misidentified as S. aureus because they cannot be differentiated easily using routine diagnostic microbiology methods. An 81-year-old man was admitted because of persistent lumbar pain and fever. Strains from his blood cultures were initially identified as methicillin-susceptible S. aureus. Enhanced computed tomography revealed an erector spinae abscess connected with the L5 transverse process, and magnetic resonance imaging of the lumbar region showed a high intensity of L1 and L5 on short tau inversion recovery. The abovementioned pathogen was also cultured from the aspiration fluid of the abscess. Therefore, the patient was diagnosed with vertebral osteomyelitis with an erector spinae abscess. We analyzed the detected strain using matrix-assisted laser desorption ionization time-of-flight mass spectrometry and whole-genome sequencing, re-identifying the strain as S. argenteus sequence type (ST)1223. Although S. argenteus ST1223 has mainly enteric pathogenicity, our case suggests its potential to invade the musculoskeletal system. Its pathogenicity was similar to or greater than that of S. aureus in both previous studies and our case. Thus, the clinical differentiation of S. argenteus and S. aureus warrants further investigation.
DOI	10.7883/yoken.JJID.2025.116
PMID	41034010