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コモリ コウジ
Komori Kouji
小森 光二 所属 東邦大学 医学部 医学科 職種 助教 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読なし |
| 表題 | Peritoneal dialysis-related peritonitis caused by Mycobacterium brisbanense: A case report and literature review. |
| 掲載誌名 | 正式名：IDCases |
| 掲載区分 | 国外 |
| 巻・号・頁 | 44,pp.e02628 |
| 著者・共著者 | Teppei Hasegawa,Daisuke Ono,Takayuki Kawamura,Yamamoto Ryo,Kohji Komori,Tetsuo Yamaguchi,Akito Maeshima,Kazuyuki Mimura,Kunihisa Tsukada,Hideaki Oka |
| 発行年月 | 2026 |
| 概要 | Mycobacterium brisbanense, a rare, rapidly growing, nontuberculous mycobacterium, is typically associated with respiratory infections. Herein, we report the first known case of peritoneal dialysis (PD)-related peritonitis caused by M. brisbanense in a male patient in his 70 s with end-stage renal disease due to chronic glomerulonephritis and renal sclerosis. Despite initial empirical treatment with cefazolin and ceftazidime for co-isolated bacteria (Staphylococcus warneri and Kocuria marina), the symptoms worsened. A subsequent acid-fast bacillus culture of the PD effluent was positive, and the microorganism was identified as M. brisbanense using time-of-flight mass spectrometry and whole-genome sequencing. Antibiotic susceptibility testing revealed susceptibility to all the following administered agents. The patient was successfully treated by PD-catheter removal and intravenous administration of amikacin, imipenem/cilastatin, and oral azithromycin for 40 days, followed by oral azithromycin and sitafloxacin for 153 days. M. brisbanense is a potential opportunistic pathogen in PD-related peritonitis that requires tailored antimicrobial therapy. |
| DOI | 10.1016/j.idcr.2026.e02628 |
| PMID | 42253892 |