ワカバヤシ ムネヒロ   Wakabayashi Munehiro
  若林 宗弘
   所属   東邦大学  医学部 医学科(大森病院)
   職種   助教
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 A phase II study of intrapatient dose escalation of biweekly trifluridine/tipiracil plus bevacizumab for colorectal cancer (E-BiTS study)
掲載誌名 正式名:ESMO Open
ISSNコード:2059-7029
掲載区分国外
巻・号・頁 10(9)
著者・共著者 M Wakabayashi†, H Taniguchi, A Makiyama, Y Sunakawa, H Takeda, K Arimizu, Y Okumura, C Inagaki, S Mitani, T Kudo, S Yuki, N Akazawa, C Kudo, K Mori, T Matsuda†, K Muro
担当区分 筆頭著者
発行年月 2025/08/28
概要 E-BiTS study was conducted to evaluate the feasibility and clinical impact of intrapatient dose escalation of biweekly FTD/TPI plus BEV for patients with refractory metastatic colorectal cancer (mCRC). Intrapatient dose escalation of biweekly FTD/TPI plus BEV was feasible and well tolerated and may enhance the efficacy of refractory mCRC treatment. Nonetheless, further studies are warranted to validate this individualized dosing strategy.