アワヤ　トオル   Awaya Toru   粟屋　徹    所属   東邦大学  医学部 医学科（大橋病院）    職種   准修練医
論文種別	原著
言語種別
査読の有無	査読なし
表題	A Possibility of Vasospastic Angina after mRNA COVID-19 Vaccination
掲載誌名	正式名：Vaccines ISSNコード：/2076-393X
出版社	MDPI AG
巻・号・頁	10(12),1998-1998頁
著者・共著者	Toru Awaya,Masao Moroi,Fuminori Nakamura,Satoru Toi,Momoko Wakiya,Yoshinari Enomoto,Taeko Kunimasa,Masato Nakamura
担当区分	筆頭著者,責任著者
発行年月	2022/11/24
概要	We report a case of vasospastic angina (VSA) following COVID-19 mRNA vaccination. Despite the widespread occurrence of myocarditis, there have been few reports of post-vaccinal VSA. A 41-year-old male patient was referred for chest pain at rest following mRNA vaccination; he had never experienced chest pain prior to vaccination. He was diagnosed by an acetylcholine (Ach) provocation test that showed multivessel vasospasm. After the initiation of treatment with a calcium channel blocker and nitrate, no further exacerbation of chest pain was observed. To our knowledge, this constitutes the first reported case of VSA proven by Ach provocation test after COVID-19 vaccination. The vaccination may increase coronary artery spasticity. VSA should be ruled out in post-vaccine new onset resting chest pain.
DOI	10.3390/vaccines10121998
ORCIDのPut Code	138280161
PermalinkURL	https://www.mdpi.com/2076-393X/10/12/1998/pdf