アワヤ　トオル   Awaya Toru   粟屋　徹    所属   東邦大学  医学部 医学科（大橋病院）    職種   准修練医
論文種別	原著
言語種別
査読の有無	査読なし
表題	What Should We Do after the COVID-19 Vaccination? Vaccine-Associated Diseases and Precautionary Measures against Adverse Reactions
掲載誌名	正式名：Vaccines ISSNコード：/2076-393X
出版社	MDPI AG
巻・号・頁	10(6),866-866頁
著者・共著者	Toru Awaya,Masao Moroi,Yoshinari Enomoto,Taeko Kunimasa,Masato Nakamura
担当区分	筆頭著者,責任著者
発行年月	2022/05/28
概要	COVID-19 vaccines have been used to counteract the global COVID-19 pandemic. While these are effective, adverse reactions have been reported, such as injection-site pain, muscle ache, fever, palpitation, and chest discomfort. The release of inflammatory cytokines, such as interleukin (IL)-6 and IL-1β, is a potential mechanism for post-vaccine side-effects. Chest discomfort after the vaccination, including myocarditis and acute coronary syndrome, is a particularly serious adverse reaction. It is important to be familiar with the differential diagnoses of chest discomfort and organ-specific diseases associated with COVID-19 vaccines as the preparation for booster shots and vaccinations among children aged 5–11 years begins. High-intensity exercise, alcohol, tobacco smoking, and baths promote inflammatory cytokines, such as IL-6, which may exacerbate the adverse reactions after vaccination. Japanese data show that deaths during baths are the most common for several days after mRNA vaccination. Additionally, alcohol and tobacco smoking were identified as predictive factors of lower antibody titers after vaccination. In this review, we aimed to provide a few recommendations to prevent vaccine-associated disease.
DOI	10.3390/vaccines10060866
ORCIDのPut Code	138280159
PermalinkURL	https://www.mdpi.com/2076-393X/10/6/866/pdf