スズキ　ノリユキ   Suzuki Noriyuki   鈴木　紀行    所属   東邦大学  薬学部 薬学科    職種   教授
論文種別	総説
言語種別	英語
査読の有無	査読あり
招待の有無	招待あり
表題	Recent advances in copper analyses by inorganic mass spectrometry.
掲載誌名	正式名：Journal of clinical biochemistry and nutrition ISSNコード：09120009/18805086/09120009
掲載区分	国外
巻・号・頁	71,pp.2-6
著者・共著者	Y. Ogra, Y. Tanaka, N. Suzuki
担当区分	最終著者
発行年月	2022/07/01
概要	Copper (Cu) participates in the biological redox reaction in the body, and its deficiency is fatal to the body. At the same time, Cu is extremely toxic when it exists in excess. Thus, the body has to tightly and spatiotemporally regulate the concentration of Cu within a physiological range by several groups of Cu-regulating proteins. However, entire mechanisms underlying the maintenance of Cu homeostasis in body and cells have not fully understood. It is necessary to analyze Cu itself in a body and in a cell to reveal the Cu homeostasis. In this review, recent advances in the analytical techniques to understand the Cu metabolism such as speciation, imaging and single-cell analysis of Cu were highlighted.