フルタ トシアキ   Furuta Toshiaki
  古田 寿昭
   所属   東邦大学  理学部 生物分子科学科
   職種   教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 A clickable caging group as a new platform for modular caged compounds with improved photochemical properties
掲載誌名 正式名:Chemical Communications
掲載区分国外
巻・号・頁 55(4),pp.451-454
著者・共著者 A. Z. Suzuki, R. Sekine, S. Takeda, R. Aikawa, Y. Shiraishi, T. Hamaguchi, H. Okuno, H. Tamamura, T. Furuta,
担当区分 最終著者,責任著者
発行年月 2019/01/14
概要 A 6-bromo-7-hydroxycoumarin-4-ylmethyl (Bhc) caged compound having a click-modifiable chemical handle was designed and synthesized. This molecule was applied to the synthesis of modular caged paclitaxels (PTXs) in which additional functional units could be easily installed. This system was used to prepare water-soluble caged PTXs with improved photolysis efficiencies.