カミヤ コウヘイ
Kamiya Kohei
神谷 昂平 所属 東邦大学 医学部 医学科(大森病院) 職種 講師 |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Prognostic value of post-treatment (18)F-FDG PET/CT for advanced head and neck cancer after combined intra-arterial chemotherapy and radiotherapy. |
掲載誌名 | 正式名:Chinese journal of cancer research = Chung-kuo yen cheng yen chiu ISSNコード:10009604 |
出版社 | CHINESE JOURNAL CANCER RESEARCH CO |
巻・号・頁 | 26(1),pp.30-7 |
著者・共著者 | Kimiteru Ito,Keigo Shimoji,Yoko Miyata,Kouhei Kamiya,Ryogo Minamimoto,Kazuo Kubota,Momoko Okasaki,Miyako Morooka,Jyunkichi Yokoyama |
発行年月 | 2014/02 |
概要 | OBJECTIVE: To clarify the prognostic value of post-treatment (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) in patients with advanced head and neck squamous cell carcinoma (HNSCC) after combined intra-arterial chemotherapy and radiotherapy (IACR). METHODS: Thirty-six patients with HNSCC who underwent IACR were recruited. The period from the end of IACR to the last post-treatment (18)F-FDG PET/CT examination was 8-12 weeks. Both patient-based and lesion-based analyses were used to evaluate the PET/CT images. For lesion-based analysis, 36 regions (12 lesions of recurrences and 24 scars at primary sites) were selected. The Kaplan-Meier method was used to assess the overall survival (OS) stratified by (18)F-FDG uptake or visual interpretation results. RESULTS: Twelve patients with recurrence were identified by six months after IACR. The sensitivity and specificity in the patient-based analysis were 67% (8/12) and 88% (21/24), respectively. The mean OS was estimated to be 12.1 months (95% CI, 6.3-18.0 months) for the higher maximum standardized uptake value (SUVmax) group (n=7) and 44.6 months (95% CI, 39.9-49.3 months) for the lower SUVmax gr |
DOI | 10.3978/j.issn.1000-9604.2014.01.06 |
PMID | 24653624 |