カミヤ コウヘイ   Kamiya Kohei
  神谷 昂平
   所属   東邦大学  医学部 医学科(大森病院)
   職種   講師
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Prognostic value of post-treatment (18)F-FDG PET/CT for advanced head and neck cancer after combined intra-arterial chemotherapy and radiotherapy.
掲載誌名 正式名:Chinese journal of cancer research = Chung-kuo yen cheng yen chiu
ISSNコード:10009604
出版社 CHINESE JOURNAL CANCER RESEARCH CO
巻・号・頁 26(1),pp.30-7
著者・共著者 Kimiteru Ito,Keigo Shimoji,Yoko Miyata,Kouhei Kamiya,Ryogo Minamimoto,Kazuo Kubota,Momoko Okasaki,Miyako Morooka,Jyunkichi Yokoyama
発行年月 2014/02
概要 OBJECTIVE: To clarify the prognostic value of post-treatment (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) in patients with advanced head and neck squamous cell carcinoma (HNSCC) after combined intra-arterial chemotherapy and radiotherapy (IACR). METHODS: Thirty-six patients with HNSCC who underwent IACR were recruited. The period from the end of IACR to the last post-treatment (18)F-FDG PET/CT examination was 8-12 weeks. Both patient-based and lesion-based analyses were used to evaluate the PET/CT images. For lesion-based analysis, 36 regions (12 lesions of recurrences and 24 scars at primary sites) were selected. The Kaplan-Meier method was used to assess the overall survival (OS) stratified by (18)F-FDG uptake or visual interpretation results. RESULTS: Twelve patients with recurrence were identified by six months after IACR. The sensitivity and specificity in the patient-based analysis were 67% (8/12) and 88% (21/24), respectively. The mean OS was estimated to be 12.1 months (95% CI, 6.3-18.0 months) for the higher maximum standardized uptake value (SUVmax) group (n=7) and 44.6 months (95% CI, 39.9-49.3 months) for the lower SUVmax gr
DOI 10.3978/j.issn.1000-9604.2014.01.06
PMID 24653624