カミヤ　コウヘイ   Kamiya Kohei   神谷　昂平    所属   東邦大学  医学部 医学科（大森病院）    職種   講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Semi-automatic volumetry of cortical tubers in tuberous sclerosis complex.
掲載誌名	正式名：Japanese journal of radiology ISSNコード：18671071
出版社	SPRINGER
巻・号・頁	31(4),pp.253-61
著者・共著者	Yasuhiro Nakata,Noriko Sato,Ayako Hattori,Kimiteru Ito,Yukio Kimura,Kouhei Kamiya,Yoko Shigemoto,Eiji Nakagawa,Masayuki Sasaki,Kuni Ohtomo
発行年月	2013/04
概要	PURPOSE: The purpose of this study was to examine the relationship between the volume and number of tubers and the age at seizure onset in patients with tuberous sclerosis complex. We also examined the relationship between the volume and number of cyst-like tubers and the age at seizure onset. MATERIALS AND METHODS: We retrospectively studied 23 patients with TSC (16 males and 7 females, mean age 12.4 ± 9.5 years). Routine structural MR-imaging data analysis was performed using QBrain. Total brain volume, total tuber volume, and the number of tubers were measured semi-automatically. Additionally, the total volume and the number of only cyst-like tubers were measured. The tuber/brain proportion (TBP) and the cyst-like tuber/brain proportion (cTBP) were calculated, and these were compared with the age at seizure onset. The numbers of tubers and cyst-like tubers were also compared with the age at seizure onset. RESULTS: For both TBP and the number of tubers, a significant negative correlation with age at seizure onset was identified (ρ = -0.69, p<0.01 and ρ = -0.56, p<0.01). No significant correlation of cTBP or the number of cyst-like tubers with age at seizure onset was ident
DOI	10.1007/s11604-012-0178-0
PMID	23377764