カミヤ　コウヘイ   Kamiya Kohei   神谷　昂平    所属   東邦大学  医学部 医学科（大森病院）    職種   講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	SISCOM technique with a variable Z score improves detectability of focal cortical dysplasia: a comparative study with MRI.
掲載誌名	正式名：Annals of nuclear medicine ISSNコード：09147187
出版社	SPRINGER
巻・号・頁	26(5),pp.397-404
著者・共著者	Yukio Kimura,Noriko Sato,Kimiteru Ito,Kouhei Kamiya,Yasuhiro Nakata,Yuko Saito,Hiroshi Matsuda,Kenji Sugai,Masayuki Sasaki,Hideharu Sugimoto
発行年月	2012/06
概要	OBJECTIVE: Focal cortical dysplasia (FCD) is one of the causes of epilepsy, but its diagnosis by MRI remains difficult. The purpose of this study was to evaluate the use of subtraction ictal SPECT coregistered to MRI (SISCOM) and MRI to detect the epileptogenic focus in patients with FCD. METHODS: MRI and SISCOM findings of 20 patients with pathologically proven FCD were retrospectively reviewed. MRI was visually assessed for detecting FCD. SISCOM was evaluated by a new method selecting a higher standard deviation (Z score) area as the epileptogenic focus. We scored the detectability in both SISCOM and MRI while referring to the pathology. RESULTS: Sixteen patients agreed with pathology on SISCOM and 14 patients on MRI. Although MRI could not point out foci in two cases of FCD type I, SISCOM could do so in both of them. A combined diagnosis of SISCOM and MRI agreed with the pathology in 18 patients. CONCLUSIONS: Narrowing the target by elevating the Z score on SISCOM seems to be an appropriate method to detect the foci without the need for expertise of radiologists. We recommend this combined method of SISCOM and MRI for presurgical evaluation in patients with FCD.
DOI	10.1007/s12149-012-0585-4
PMID	22427267