イシダ　マサヒロ   Ishida Masahiro   石田　政弘    所属   東邦大学  医学部 医学科（大橋病院）    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Photoreceptor inner and outer segment layer thickness inmultiple evanescent white dot syndrome
掲載誌名	正式名：GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY ISSNコード：0721832X
出版社	SPRINGER
巻・号・頁	252(10),pp.1645-1651
著者・共著者	Rei Arai,Itaru Kimura,Yutaka Imamura,Kei Shinoda,Celso Soiti Matsumoto,Keisuke Seki,Masahiro Ishida,Akira Murakami,Atsushi Mizota
発行年月	2014/10
概要	Purpose To evaluate the photoreceptor inner and outer segment layer thickness in eyes with MEWDS. Design Prospective, non-comparative, observational case series. The follow-up duration was 4 months.Methods Four women were diagnosed with unilateral MEWDS. The ages of the patients were 25, 24, 35, and 40 years. The retinal microstructure was assessed by spectral-domain optical coherence tomography (SD-OCT). The thickness of the photoreceptor inner (IS) and outer (OS) segments and sum of them (IS + OS) at the fovea were analyzed.Results The visual acuity was reduced in three of four eyes at the acute phase. SD-OCT showed that the border of IS and OS (IS/OS) line and the cone outer segment tips (COST) line in the macula area were not detected in all four eyes. The IS + OS thickness was 50.3 +/- 5.6 mu m and that of the healthy fellow eyes was 73.5 +/- 7.0 mu m (n = 4 eyes). The thickness of the IS was 27.8 +/- 2.6 mu m and that of the OS was 45.8 +/- 7.3 mu m. In all eyes, there was a spontaneous improvement of the visual acuity. SD-OCT showed a recovery of only the IS/OS line in the macular area, but the COST line was not visible in three cases. The mean IS + OS thickness increased
DOI	10.1007/s00417-014-2747-7
PMID	25081025