イシダ　マサヒロ   Ishida Masahiro   石田　政弘    所属   東邦大学  医学部 医学科（大橋病院）    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Assessment of Glaucomatous Changes in Subjects with High Myopia Using Spectral Domain Optical Coherence Tomography
掲載誌名	正式名：INVESTIGATIVE OPHTHALMOLOGY&VISUAL SCIENCE ISSNコード：01460404
出版社	ASSOC RESEARCH VISION OPHTHALMOLOGY INC
巻・号・頁	52(2),pp.1098-1102
著者・共著者	Takuhei Shoji,Hiroki Sato,Masahiro Ishida,Masaru Takeuchi,Etsuo Chihara
発行年月	2011/02
概要	PURPOSE. To evaluate the diagnostic ability to detect glaucoma in highly myopic eyes using spectral domain-optical coherence tomography (SD-OCT) parameters in a cross-sectional comparative study.METHODS. A total of 82 patients with high myopia (<= -5 D) presented between April 2008 and August 2009. Subjects comprised 31 participants with high myopia but not perimetric glaucoma (no glaucoma group) and 51 patients with high myopia and concomitant perimetric glaucoma (glaucoma group). Ganglion cell complex (GCC), circumpapillary retinal nerve fiber layer (p-RNFL), and disc configuration parameters were obtained from algorithms of the SD-OCT system and subsequently compared. Receiver operating characteristics curves were constructed for each measurement parameter, and areas under the curves (AUCs) were compared.RESULTS. All optic nerve fiber head, except disc area, and GCC parameters differed significantly between groups (P< 0.05). The largest AUCs from disc configuration, circumpapillary RNFL, and GCC parameters were 0.844 (C/D vertical), 0.826 (RNFL average), and 0.954 (global loss volume [GLV]), respectively. GLV was significantly better for detecting perimetric glaucoma th
DOI	10.1167/iovs.10-5922
PMID	21051712