カワタ　タケフミ   Kawata Takefumi   川田　健文    所属   東邦大学  理学部 生物学科    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Implications of expansin-like 3 gene in Dictyostelium morphogenesis
掲載誌名	正式名：SpringerPlus
出版社	Springer
巻・号・頁	4,pp.190
著者・共著者	Kawata, T＊†, Nakamura, Y†, Saga, Y†, Iwade, Y†, Ishikawa, M†, Sakurai, A† and Shimada, N†
担当区分	筆頭著者
発行年月	2015/04
概要	Dictyostelium harbors multiple expansin-like genes with generally unknown functions. Thus, we analyzed the expansin-like 3 (expL3) gene and found that its expression was reduced in a null mutant for a STATa gene encoding a transcription factor. The expression of expL3 was developmentally regulated and its transcript was spliced only in the multicellular stages. The expL3 promoter was activated in the anterior prestalk region of the parental strain and downregulated in the STATa null slug, although the expL3 promoter was still expressed in the prestalk region. The expL3 overexpressing strain exhibited delayed development and occasionally formed an aberrant structure, i.e., a fruiting body-like structure with a short stalk. The ExpL3-myc protein bound cellulose.
DOI	doi:10.1186/s40064-015-0964-0