ササキ　ヨウスケ   Sasaki Yosuke   佐々木　陽典    所属   東邦大学  医学部 医学科（大森病院）    職種   教授
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Meningitis associated with strongyloidiasis in an area endemic for strongyloidiasis and human T-lymphotropic virus-1: a single-center experience in Japan between 1990 and 2010
掲載誌名	正式名：Infection
出版社	Springer
巻・号・頁	41,pp.1189-1193
著者・共著者	Sasaki Y, Taniguchi T, Kinjo M, McGill. RL, McGill AT, Tsuha T, Shiiki S
担当区分	筆頭著者,責任著者
発行年月	2013/06
概要	Meningitis caused by enteric flora is a known complication of strongyloidiasis, and human T-lymphotropic virus-1 (HTLV-1) predisposes individuals to severe strongyloidiasis. We reviewed the clinical features of bacterial meningitis associated with strongyloidiasis seen at a single center in subtropical Japan, in an area endemic for both strongyloidiasis and HTLV-1. We found 33 episodes in 21 patients between 1990 and 2010. The results were remarkable for the high incidence of meningitis due to Gram-positive cocci (27.3 %), especially Streptococcus bovis, and culture-negative cases (42.4 %). Given the high incidence of Gram-positive meningitis, a modified approach to corticosteroid use would be advisable in areas where strongyloidiasis is endemic, due to the potentially adverse consequences of glucocorticoid therapy.
DOI	10.1007/s15010-013-0483-2