リ　ギ   Li Wei   李　巍    所属   東邦大学  薬学部 薬学科    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Biologically active triterpenoid saponins from Ardisia japonica
掲載誌名	正式名：Journal of natural products 略　 称：J Nat Prod ISSNコード：01633864
巻・号・頁	70(2),pp.179-187
著者・共著者	Xiaolong Chang, Wei Li, Zhonghua Jia, Tadaaki Satou, Shinji Fushiya, Kazuo Koike
担当区分	2nd著者
発行年月	2007
概要	Eleven new triterpenoid saponins, ardisianosides A (1)(I), B (2), C (4), D (5), E (6), F (7), G (15), H (16), I (17), J (18), and K (19), together with 10 known saponins, were isolated from the whole plants of Ardisia japonica. The structures of the new saponins were established on the basis of extensive 1D and 2D NMR and MS studies coupled with chem. degrdns. The cytotoxic activities of saponins 1-21 are reported against three human cancer cell lines, namely, HL-60 myeloid leukemia, KATO-III stomach adenocarcinoma, and A549 lung adenocarcinoma cells.