オザキ　イサム   Ozaki Isamu   尾﨑　勇    所属   東邦大学  医学部 医学科    職種   研究員（寄付講座）
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	High-frequency transcutaneous electrical nerve stimulation (TENS) differentially modulates sensorimotor cortices: An MEG study
掲載誌名	正式名：CLINICAL NEUROPHYSIOLOGY ISSNコード：1388-2457
出版社	ELSEVIER IRELAND LTD
巻・号・頁	121(6),pp.939-944
著者・共著者	Takenobu Murakami,Ryosuke Takino,Isamu Ozaki,Tomoaki Kimura,Yoshinobu Iguchi,Isao Hashimoto
発行年月	2010/06
概要	Objective: Transcutaneous electrical nerve stimulation (TENS) affects excitability of the central motor system as well as the somatosensory system. To determine whether TENS has influence on excitability in the sensorimotor cortices of TENS-treated finger muscle, we investigated magnetoencephalogram associated with voluntary, self-paced finger movement before and after TENS. Methods: High-frequency TENS was applied on the extensor digitorum muscle for 15 min. Subjects underwent alternate middle finger and thumb extension movements before and after the TENS. We recorded movement-related cortical magnetic field (MRCF) associated with TENS-treated middle finger movement and that from untreated thumb movement. Results: The current source for motor field (MF) was located in the pre-central motor cortex and anteriorly-oriented, and that for motor evoked field one (MEF1) was found in the post-central somatosensory cortex and posteriorly-oriented. The amplitude of MF for TENS-treated middle finger movement decreased but unchanged for untreated thumb movement after TENS. The amplitude of MEF1 decreased for either finger movement after TENS. Conclusion: High-frequency TENS to the forearm muscle modulates excitability of the limited area of motor cortex but wider area of primary somatosensory cortex. Significance: High-frequency TENS to the forearm muscle modulates excitability of the primary somatosensory cortex and motor cortex in a different manner. (C) 2010 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
DOI	10.1016/j.clinph.2010.01.011
PMID	20149725