ニシオ　ジュンコ   Nishio Junko   西尾　純子    所属   東邦大学  医学部 医学科    職種   准教授
論文種別	原著
言語種別	日本語
査読の有無	査読なし
表題	[Case of dermatomyositis complicated with massive pleural effusion that preceded the myopathy].
掲載誌名	正式名：Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology ISSNコード：0911-4300
掲載区分	国内
巻・号・頁	25(3),270-6頁
著者・共著者	Hideyuki Iwai,Ryuji Koike,Jun Ogawa,Takahiko Sugihara,Hiroyuki Hagiyama,Kenji Nagasaka,Yoshinori Nonomura,Junko Nishio,Toshihiro Nanki,Rieko Tsubata,Hitoshi Kohsaka,Tetsuo Kubota,Nobuyuki Miyasaka
発行年月	2002/06
概要	A 36-year-old man was admitted to a hospital with complaints of fever, polyarthralgia and dyspnea. Erythema was observed on his face, extensor surface of the fingers and extremities, and a chest X-ray revealed massive bilateral pleural effusion. He had no sign of myopathy at this point. Pleural fluid was proved to be exudative and contained extremely high levels of hyaluronic acid. He was also complicated with interstitial pneumonitis and was given a pulse therapy with methyl prednisolone followed by daily administration of 55 mg prednisolone (PSL). Twenty days after the commencement of the therapy, pleural effusion decreased but muscle weakness gradually appeared, accompanied by elevation of myogenic enzymes. Myogenic changes on electromyogram, and irregularity of the muscle fibers with slight inflammatory cell infiltrates in a biopsy specimen were demonstrated. He was transferred to our hospital, and a diagnosis of dermatomyositis was made. Later, pleural effusion waxed and waned depending on the dosage of PSL, but no other causative disorder was demonstrated by extensive examinations. This case indicates that the pleuritis could be one of the vasculitic manifestations of dermatomyositis.
PMID	16578971