リ ギ   Li Wei
  李 巍
   所属   東邦大学  薬学部 薬学科
   職種   教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Inhibitory effects of compounds from fruits of Juglans mandshurica on pancreatic lipase
掲載誌名 正式名:Journal of Natural Medicines
ISSNコード:13403443
巻・号・頁 61(2),pp.184-186
著者・共著者 Likun Han, Wei Li, Sanae Narimatsu, Lijuan Liu, Hongwei Fu, Hiromichi Okuda, Kazuo Koike
担当区分 2nd著者
発行年月 2007
概要 The water ext. of Juglans mandshurica fruit has been shown to strongly inhibit pancreatic lipase in vitro in a dose-dependent manner. The ext. was obsd. to inhibit the normal elevation in the level of plasma triacylglycerol in rats 2-4 h after oral administration of a lipid emulsion. Fourteen compds. isolated from J. mandshurica fruit were evaluated for their inhibitory activity against pancreatic lipase. Of these, 1,4,8-trihydroxynaphthalene-1-O-.beta.-D-[6'-O-(3'',4'',5''-trihydroxybenzoyl)]glucopyranoside showed the strongest inhibitory activity.